Abstract: In quest of an efficient delivery system and for accurate delivery of drug to the ailment site, various researchers focused on development of a versatile delivery system. In progression, investigations on novel materials gained spotlight to add new dimension in the delivery devices to provide a more compatible and innovative platform for drug delivery. For innovative delivery systems, biomaterials like nanocelluloses were exploited for designing various scaffolds and delivery devices like microneedles. Microneedle devices are current trends of drug delivery where nanocellulose has evolved as protagonist for delivery aspects andstrengthen the structural integrity of device. Nanocelluloses provided a wide choice for polymers to design biodegradable microneedle device. Nanocellulose