Abstract: We present a novel process to encapsulate indocyanine green (ICG) in liposomal droplets at high concentration for potential applications in image-guided drug delivery. The microencapsulation process follows two consecutive steps of droplet formation by liquid-driven coaxial flow focusing (LDCFF) and solvent removal by oil phase dewetting. These biocompatible lipid vesicles may have important applications in drug delivery and fluorescence imaging.

Zhu Z, Si T, Xu RX. Microencapsulation of indocyanine green for potential applications in image-guided drug delivery. Lab Chip. Feb 7 2015;15(3):646-9. doi:10.1039/c4lc01032a